Bio-identical Hormone Replacement Therapy: What You Need to Know


Few areas of health care are as plagued by competing claims and confusion as hormone therapy, but when approached with a holistic perspective under medical supervision, bio-identical hormone replacement therapy can be life-changing.



Conventional hormone therapy has been the subject of several high-profile news stories, and more research needs to be done on its long-term effects. Bio-identical hormones offer an alternative to conventional hormone therapy. But, because our body’s responses to hormones vary widely, it’s important to always work with a healthcare practitioner to determine the right treatment for you.


Here are some answers to common questions about bio-identical hormone therapy (BHRT).

What Is Bio-identical Hormone Therapy?


 

The chemical structure of bio-identical hormones is identical to that of the hormones your body produces naturally – hence their name. The hormones are derived from plants and can be produced in a factory or by a compounding pharmacist.


The most commonly prescribed types of bio-identical hormones are testosterone, estrogen, and progesterone. These hormones are delivered to the body in many forms, including suppositories, sprays, injections, gels, and pills.


Who Benefits From Bio-identical Hormone Therapy?


 


Both men and women may benefit from bio-identical hormone therapy. Women often start when they enter the perimenopause years to help maintain hormonal balance. Up to 2.5 million women in the US use BHRT, by some estimates two-thirds of all women taking hormonal therapy, to help with menopausal symptoms.



Men often start in their 40s, when testosterone levels start to decline.


 

What Conditions Does BHRT Help With?


 

As we age, the production of several important hormones declines. The effects of these dropping hormone levels can be profound. Women can experience:

●     Weight gain

●     Brain fog

●     Fatigue

●     Depression

●     Hair loss


●     Hot flashes


●     Foggy thinking


●     Insomnia



●     Loss of libido


●     Vaginal dryness

For men, a decline in testosterone levels results in very similar symptoms:

●     Fatigue

●     Loss of libido

●     Weight gain

●     Men can even experience hot flashes!

BHRT can reduce the systems of declining hormone levels. It can also provide some preventative protection against conditions like diabetes and osteoporosis.

 

What Are The Risks Of BHRT?


 

Although many people experience a relief from a myriad of symptoms thanks to BHRT, studies also point to possible health risks, including increased incidents of:

●     Blood clots

●     Mood problems

●     Stroke

●     Heart disease

●     Breast cancer

 


When assessing the risks of BHRT, it’s important to consider your overall health. Smokers, for example, have a higher risk of blood clots. Anyone who has been diagnosed with breast cancer in the past should avoid BHRT. The risk of heart disease or cancer may increase with age, or the longer you take BHRT.


This makes the decision whether or not to take hormones highly personal. Research shows that menopausal women benefit from an overall examination of their health when they’re prescribed BHRT. Typically, they experience more in depth, personal care during the process than they do with conventional hormone treatment – and you shouldn’t expect anything less if you consider any type of hormone therapy. 

As well, compounded bio-identical hormone therapy is not regulated by the FDA, so it’s important to work with a reputable provider. It’s generally smart to start with a low dose and see how your body responds.

 

Are There Alternatives To BHRT?


Anyone concerned about the long-term effects of BHRT, or anyone in a high-risk group, may want to explore natural alternatives for hormone support instead. Here are some effective strategies.

 

●     Include phytoestrogens in your diet. Phytoestrogens are plants that naturally contain estrogen. Good sources include:

●     Flax seed

●     Peas

●     Lentils

●     Beans

●     Soy products

●     Green tea

 


●     Eat plenty of protein and enjoy a balanced diet. Crash diets can slow testosterone production.



●     Supplement smartly. Some natural supplements have been shown to support hormone levels. As always, work with your healthcare provider.


○     Black cohosh can help ease hot flashes and other menopausal symptoms

○     Vitamin D and zinc have positive effects on testosterone.

●     Watch your alcohol intake. Alcohol can exacerbate symptoms of hormone imbalances, such as hot flashes.

●     Include strength training. Lifting weights can improve testosterone in men. Although this is less of an impact in women, strength training can improve symptoms of menopause and reduce the risk of osteoporosis.


●     Get enough sleep Hormonal imbalances can wreak havoc on sleep, but at the same time, lack of sleep can affect hormone production. Work on creating a restful evening routine to encourage sleep.



●     Watch your stress levels. Stress increases production of cortisol, and cortisol and testosterone can contradict each other – as your levels of one rise the other decreases. If it’s hard to reduce situational stress in your life, try stress-reducing activities like time in nature and meditation.


Bio-identical hormone replacement therapy can help both men and women experiencing declines in hormone production. It’s best used as part of a holistic health program to support hormones.

It’s important to work closely with experienced healthcare providers – like us! We can review treatment protocols with you, answer any questions, and develop a personalized plan tailored to you. Just give us a call!

 

 

 

Sources:





Pinkerton JV, Santoro N. Compounded bioidentical hormone therapy: identifying use trends and knowledge gaps among US women. Menopause. 2015 Sep;22(9):926-36. doi: 10.1097/GME.0000000000000420. PMID: 25692877; PMCID: PMC454772

 

Files JA, Ko MG, Pruthi S. Bioidentical hormone therapy. Mayo Clin Proc. 2011 Jul;86(7):673-80, quiz 680. doi: 10.4065/mcp.2010.0714. Epub 2011 Apr 29. PMID: 21531972; PMCID: PMC3127562.

 

Spetz AC, Fredriksson MG, Hammar ML. Hot flushes in a male population aged 55, 65, and 75 years, living in the community of Linköping, Sweden. Menopause. 2003 Jan-Feb;10(1):81-7. doi: 10.1097/00042192-200310010-00013. PMID: 12544681.

 

Pentti K, Tuppurainen MT, Honkanen R, Sandini L, Kröger H, Alhava E, Saarikoski S. Hormone therapy protects from diabetes: the Kuopio osteoporosis risk factor and prevention study. Eur J Endocrinol. 2009 Jun;160(6):979-83. doi: 10.1530/EJE-09-0151. Epub 2009 Mar 25. PMID: 19321660.

 

Gass ML, Stuenkel CA, Utian WH, LaCroix A, Liu JH, Shifren JL; North American Menopause Society (NAMS) Advisory Panel consisting of representatives of NAMS Board of Trustees and other experts in women’s health. Use of compounded hormone therapy in the United States: report of The North American Menopause Society Survey. Menopause. 2015 Dec;22(12):1276-84. doi: 10.1097/GME.0000000000000553. PMI

 

Thompson JJ, Ritenbaugh C, Nichter M. Why women choose compounded bioidentical hormone therapy: lessons from a qualitative study of menopausal decision-making. BMC Womens Health. 2017 Oct 2;17(1):97. doi: 10.1186/s12905-017-0449-0. PMID: 28969624; PMCID: PMC5625649.

 

Franco OH, Chowdhury R, Troup J, et al. Use of Plant-Based Therapies and Menopausal Symptoms: A Systematic Review and Meta-analysis. JAMA. 2016;315(23):2554–2563. doi:10.1001/jama.2016.8012

 

Canguven O, Talib RA, El Ansari W, Yassin DJ, Al Naimi A. Vitamin D treatment improves levels of sexual hormones, metabolic parameters and erectile function in middle-aged vitamin D deficient men. Aging Male. 2017 Mar;20(1):9-16. doi: 10.1080/13685538.2016.1271783. Epub 2017 Jan 11. PMID: 28074679.

 

Mazaheri Nia L, Iravani M, Abedi P, Cheraghian B. Effect of Zinc on Testosterone Levels and Sexual Function of Postmenopausal Women: A Randomized Controlled Trial. J Sex Marital Ther. 2021;47(8):804-813. doi: 10.1080/0092623X.2021.1957732. Epub 2021 Jul 27. PMID: 34311679.

 

Timón Andrada R, Maynar Mariño M, Muñoz Marín D, Olcina Camacho GJ, Caballero MJ, Maynar Mariño JI. Variations in urine excretion of steroid hormones after an acute session and after a 4-week programme of strength training. Eur J Appl Physiol. 2007 Jan;99(1):65-71. doi: 10.1007/s00421-006-0319-1. Epub 2006 Oct 19. PMID: 17051372.

 

Whittaker J, Harris M. Low-carbohydrate diets and men’s cortisol and testosterone: Systematic review and meta-analysis. Nutrition and Health. 2022;28(4):543-554. doi:10.1177/02601060221083079

 

Related Posts

Dr. Erica Daoud
DC

Board-certified chiropractor

Dr. Erica Daoud is a board-certified chiropractor with a deep passion for supporting families—especially moms and little ones—through every stage of life. She specializes in pediatric and prenatal/postnatal care, helping restore the nervous system to its highest function so children and parents can truly thrive. She is also board-certified in acupuncture, offering a holistic and well-rounded approach to health and healing.

Before becoming a chiropractor, Dr. Erica worked as a paramedic for four years, giving her a strong foundation in emergency medicine and a unique perspective on patient care. This experience fuels her calm, compassionate, and thorough approach to chiropractic and wellness care.

A proud native of Florida, she earned her bachelor’s degree in Molecular Biology and Microbiology from the University of Central Florida (Go Knights!) and completed her Doctorate of Chiropractic at Palmer College.

When she’s not in the office, you’ll likely find Dr. Erica spending time with her husband, Joe, snuggling their Yorkie, Jake, or enjoying her favorite hobbies: cross-stitching, sewing, reading, and traveling. She’s always up for a good concert or discovering a new place to explore!

Dr. Matthew Roberts
DC

Doctorate of Chiropractic from Palmer College of Chiropractic Florida in 2015.

Dr. Matthew Roberts was born and raised in Central Florida. He earned his Bachelor of Science in Biology from the University of Central Florida (Go Knights!) in 2008, and went on to receive his Doctorate of Chiropractic from Palmer College of Chiropractic Florida in 2015.

Since 2020, Dr. Matt has served as an adjunct professor at Palmer Florida, where he helps train future doctors through the preceptor program. He is well-versed in multiple chiropractic techniques, which he uses to tailor treatments to each individual’s needs. In addition, he has advanced training in internal medicine and nutrition.
Dr. Matt is passionate about identifying the root cause of health concerns rather than simply addressing symptoms. He treats patients in all stages of life—including newborns, children, adults, seniors, pregnant individuals, and those recovering from sports injuries.

Outside the office, Dr. Matt enjoys spending time with his wife, their three children, and their rescue dogs. He’s also an avid Orlando Magic fan. Dr. Matt looks forward to meeting you and your family!

Kelli Dorrough
CA, CPEP ®

Chiropractic Assistant, Brain Health
Coach, Neurofeedback & Posture
Rehab Specialist, and K-Laser
Technician

Kelli has been with Restoring Health since 2014. She is an educator, Certified Brain Health Coach, Chiropractic Assistant (CA), Certified Posture Exercise Professional (CPEP®), and Rehab Fitness Specialist. She also holds certificates in Amen Clinics’ Change Your Brain Change Your Life and Hope-Focused 3 “R” Suicide Prevention from Light University. Originally from Miami, Kelli graduated from Florida International University in 1993 receiving a Bachelor of Science degree in Education with a focus in Childhood Psychology.

Kelli has always been fascinated by the brain and how it works; consequently, her interest in EEG Biofeedback (Neuro-Biofeedback) and brain training has been a natural progression for her and her career in healthcare. Having a desire to further her education in areas of neuroscience, brain health, and the prevention of cognitive decline ultimately drew her to Light University where she received her certification as a Brain Health Coach under the tutelage of the prestigious Daniel G. Amen, MD. Kelli is now dedicated to educating clients on brain healthy principals and helping them achieve positive changes in their overall health and well being.

Kelli loves dogs and salsa dancing and is always happy to go to a Miami Dolphins football game.

Dr. Dana O’Keefe
DC, CCSP ®

Restoring Health Wellness Center
Owner/Director & Functional Medicine
Physician

Dr. Dana O’Keefe is co-founder, owner, and director of Restoring Health Holistic Wellness Center where she helps patients regain and maintain there health using a natural and holistic approach.

Dr. O’Keefe graduated Cum Laude from Palmer College of Chiropractic Florida Campus with her degree as a Chiropractic Physician, and with honors from University of Phoenix with a B.S. degree in Business Management. She has also obtained the postgraduate designation of Certified Chiropractic Sports Physician® (CCSP®) by the American Chiropractic Board of Sports Physicians™. This certification is specific to physical fitness and the evaluation and treatment of injuries encountered in sports.

Her extensive education as a Functional Medicine Physician Board qualifications include: Diplomate of the American Board of Chiropractic Internists (DABCI), Diplomate of the American Board of Clinical Nutrition (DACBN), and Certified Functional Medicine Physician (CFMP.) She prescribes, advanced lab work to support her evaluation and determination of the underlying cause of various health issues. Through the use of appropriate diet, nutrition, lifestyle modifications, and exercise, she guides her patients in their journey towards abundant health.

As a Chiropractic Physician, Dr. O’Keefe uses a variety of techniques including: Instrument Adjusting, Myofascial Release, Flexion-Distraction, and Activator techniques. She is a member of the Florida Chiropractic Association and holds additional certifications in Class IV K-Laser therapy, Graston adhesion release technique, Kinesiology sports taping, as well as TPI and Postural Rehabilitation for athletes.

Prior to her doctoral studies, Dr. O’Keefe enjoyed an extensive career within the dance community as a choreographer and dance instructor. This background gives her a unique perspective when assessing injuries, postural insufficiencies, and kinetic chain dysfunctions. Her past career experiences, coupled with substantial education in anatomy, physiology, and nutrition have strongly influenced her resolve to help her patients remain active and healthy.

Dr. O’Keefe’s hobbies include: Cooking, hiking, biking, and equestrian sports